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Kluveromyces lactisSimilar to S cerevisiae
2021-04-13

Kluveromyces lactisSimilar to S. cerevisiae, K. lactis is a facultative anaerobic respiratory yeast, which lacks Complex I in its mitochondrial respiratory chain. However, both yeasts differ regarding their respiratory-fermentative metabolism as K. lactis exhibits a greater use of the pentose phosph
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br Subjects and methods br Results br
2021-04-13

Subjects and methods Results Discussion In the present study, we found significantly increased CSF levels of IL-4, IL-5, IL-9, IL-10, TNF-α, CXCL8/IL-8, and VEGF-A together with significantly higher detection rates of IL-6, GM-CSF, PDGF-BB and IL-1ra in IHP patients compared with OND patien
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In recent years the use of
2021-04-13

In recent years, the use of liquid chromatography/tandem mass spectrometry (LC–MS/MS) has become a preferred approach to measure drugs and metabolites in biological fluids due to its very high selectivity and sensitivity [17], [18], [19], [20], [21], [22], [23], [25], [30]. The great sensitivity of
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As suggested by previous data we identified that
2021-04-13

As suggested by previous data [45], we identified that the N-terminal and C-terminal domains of DDX3 were enriched in intrinsically disordered regions (Fig. 6). We also found that this characteristic was conserved in the external domains of several homologs of DDX3 (from yeast to human) and all desc
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On close inspection the pattern shows large areas
2021-04-13

On close inspection, the pattern shows large areas of very low point intensity where hardly any trees can be found. Anecdotal knowledge reveals that these regions are covered by a swamp, where the tree species is known to be very unlikely to grow, independent of local soil covariates and topography.
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Stable isotope studies applied to skeletal
2021-04-13

Stable isotope studies, applied to skeletal remains of early Pacific populations, have shown a trend toward a horticultural diet with temporal variation in response to local environmental conditions (Field et al., 2009; Kinaston and Buckley, 2013; Valentin et al., 2010, Valentin et al., 2014; Kinast
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Concanamycin A It is generally thought that the nature
2021-04-13

It is generally thought that the nature of a memorial and the meaning attributed to it Concanamycin A by a tourist determines, at least in part, the behaviour that is socially appropriate (Mayo, 1988). Duncan (1995) argues however, that certain places are structured in such a way that they facilita
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Semantics play an important role in software component based
2021-04-13

Semantics play an important role in software component-based development as they improve components identification, selection and integration through, among others, the use of ontologies (Kaur and Mishra, 2017). Analogously, they allow to improve discovery, composition and reuse in the context of We
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The COMT gene is involved
2021-04-13

The COMT gene is involved in numerous psychological and physiologic processes, including modulation of pain. Polymorphisms in this gene have also been associated with many painful conditions, including pain sensitivity in children. Bivariate analysis demonstrated that individuals with heterozygous C
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In the current study we monitored different groups
2021-04-13

In the current study, we monitored different groups at risk for CMV reactivation. Similar to the findings from other groups, we observed CMV-reactivations with high-level viremia mostly during the first three months after alloHSCT only in the (D−/R+) and (D+/R+) group [[23], [24]]. Increasing IFN‐γ
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Notably HSP expression is under control of the
2021-04-13

Notably, HSP27 expression is under control of the tetrameric form of CK2 holoenzyme, as knockout or knockdown of the β regulatory subunit alone reproduces the same effects of targeting the α/α′ catalytic subunits. This observation discloses the possibility to use more specific drugs that affects on
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Gastrointestinal tone can be effectively modulated by cholin
2021-04-13

Gastrointestinal tone can be effectively modulated by cholinesterase inhibitors. As parasympathetic fibers release 11021 to contract the circular and longitudinal intestinal muscles, AChE inhibition can facilitate those actions. Postoperative ileus (delayed gastric emptying after surgery) can arise
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Introduction Hematopoietic stem cells HSCs in the adult bone
2021-04-12

Introduction Hematopoietic stem 7340 receptor (HSCs) in the adult bone marrow (BM) provide all types of blood cells throughout life, while also self-renewing to maintain blood homeostasis. Blood/marrow stem cell transplantation is the most advanced method to cure patients suffering from hematologi
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Our results indirectly support the combination
2021-04-12

Our results indirectly support the combination of resveratrol and hesperatin treatment for PDN, as this induces GLO1 activity in patients (Xue et al., 2016), as well as metformin, an FDA-approved anti-diabetic treatment, which acts as an MG scavenger to reduce MG levels in type 2 diabetic patients (
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Most remarkably an essentially identical collagen binding
2021-04-12

Most remarkably, an essentially identical collagen-binding mode to DDR2 is employed by SPARC, an α-helical matricellular protein unrelated to DDR2 that also recognizes the GVMGFO motif in collagen (Giudici et al., 2008, Hohenester et al., 2008). The convergence of binding mechanisms suggests that th
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